Steroid Report

Italian cyclist Marta Bastianelli tested positive for a banned stimulant. She tested positive for the diet drug fenfluramine in a doping control conducted by the International Cycling Union (UCI) at the “Under-23 World Championships” in Verbania, Italy on July 5, 2008.

Bastianelli claims she never knowingly ingested a banned substance. She admitted to her obsession with weight control stating “I wanted to lose weight, like any girl.” She consulted with her doctor to find weight loss products that were not on the WADA banned substance list. Her doctor prescribed the drug Benfluorex. Benfluorex is an anti-diabetic drug that improves insulin sensitivity and glycemic control; as such it is often prescribed for weight loss. Benfluorex is not on the WADA banned substance list but it is structurally similar to Fenfluramine (which is listed) Read the rest of this entry »

Swimmer Jessica Hardy has withdrawn from the United States Olympic Team bound for the 2008 Beijing Olympics after testing positive for low levels of the long-acting beta-2 adrenergic agonist (LABA) clenbuterol. Hardy maintains that she never knowingly or unintentionally consumed clenbuterol or any other banned susbtance.

The question of why and how clenbuterol appeared in Jessica Hardy’s sample remains a mystery. Was Hardy simply caught doping? Or were the “dietary supplements” used by Hardy contaminated or spiked with the banned substance clenbuterol? The supplement company Advocare was cited as one of the brands of dietary supplements used by Jessica Hardy. Read the rest of this entry »

Spiropent (Promeco) clenbuterol hydrochloride

I am disappointed by the mainstream media coverage of Olympic swimmer Jessica Hardy’s failed drug test for clenbuterol (an asthma medication).

NBC was apparently the first news organization to identify the banned substance as clenbuterol. They did not elaborate on the drug other than to identify it as a “stimulant” which was of course very misleading.

Clenbuterol was not identified as an asthma medication. It was not revealed that numerous other Olympic swimmers are permitted to use similar asthma drugs as long as they have a therapeutic use exemption (TUE). In all fairness to Jessica Hardy, this information should be provided at the outset to provide the appropriate context for any story about her positive test.

Washington Post Staff Writer Amy Shipley regularly writes about doping in sports, so I was very disappointed that Shipley failed to specifically identify clenbuterol as an asthma medication. She did not mention that other Olympic swimmers are allowed to use similar asthma drugs. In fact, there was not a single instance of the word ‘asthma’ in her 600+ word article.  Read the rest of this entry »

Swimmer Jessica Hardy tests positive for clenbuterol

U.S. Olympic swimmer Jessica Hardy tested positive for the asthma medication Clenbuterol in both A and B samples at the U.S. Olympic Trials in Omaha, Nebraska on July 1st and July 4, 2008. Clenbuterol is a bronchodilator belonging to a class of drugs known as beta-2 adrenergic agonists or long-acting beta-2 adrenergic agonist (LABA) . Clenbuterol is similar to Albuterol and Salmeterol which are also LABAs.

It is well-known that a high percentage of elite swimmers have exercise-induced asthma. It is also known that most asthmatic swimmers competing in the Olympics have therapeutic use exemptions (TUEs) to use beta-2 agonists like albuterol, formoterol, salbutamol, salmeterol and terbutaline for therapeutic purposes.

The amazing swimmer Dara Torres makes no secret of her use of albuterol and formoterol; these are two different beta-2 agonists (LABAs). She probably tests positive for these substances on a regular basis too since United States Anti-Doping Agency (USADA) tests her frequently due to her participation in Project Believe. Read the rest of this entry »

John Fahey drinks a drug that is on the WADA banned substance list

Roche Pharmaceuticals quickly rejected claims that Roche planted secret molecule in Mircera which allowed for detection of the CERA class drug at the 2008 Tour de France. John Fahey, WADA president, told the Australian Broadcasting Company about the addition of the molecule that made it easy for drug testers to detect use of the performance enhancing drug.

Roche Pharmaceuticals spokesperson, Martina Rupp, strongly denied the addition of any special molecule to Mircera in an email response made within hours of Fahey statements.

“The information that a special molecule has been added to Mircera is wrong,” Rupp said in an e-mail. Read the rest of this entry »

Switzerland Roche Pharmaceuticals

John Fahey, president of the World Anti-Doping Agency (WADA), has revealed they are cooperating with Roche Pharmaceuticals to secretly add a “traceable molecule” to drugs likely to have performance enhancing effects in athletes. This was how AFLD was able to detect the previously-undetectable Mircera (CERA) in Riccardo Ricco’s sample at the 2008 Tour de France. Roche manufacures at least two PEDs used by cyclists – Mircera and NeoRecormon. Drug-tested athletes have been given notice to avoid using products manufactured by Roche Pharmaceuticals.

It seems that WADA is no longer interested in developing anti-doping tests that actually detect performance enhancing drugs (PEDs); this is understandable since serious flaws in their anti-doping tests are revealed again and again. Instead, WADA apparently believes the future of anti-doping efforts lies in anti-doping agencies cooperation with pharmaceutical companies to secretly add “traceable molecules” and “trojan molecules” (“Ricco caught by secret doping molecule: WADA chief,” July 23).

In the development of that particular substance, close cooperation occurred between WADA and the pharmaceutical company Roche Pharmaceuticals so that there was a molecule placed in the substance well in advance that was always going to be able to be detected once a test was taken,” Mr Fahey said.

Wow. I wonder what is more deplorable – athletes using performance enhancing drugs OR multi-national pharmaceutical companies secretly adding traceable molecules to consumer products and intentionally hiding this ingredient by failing to disclose it on the label? Read the rest of this entry »

Riccardo Ricco anti-dopage

Widespread doping continues in cycling despite recent proclamations by Olivier Rabin, the science director for World Anti-Doping Agency (WADA), and Pierre Bordry, the head of the French Anti-Doping Agency (AFLD), that they are practically on the verge of eliminating doping from cycling.

The testosterone doping test is flawed. The EPO test is flawed in more ways than one. Peptide hormones such as human growth hormone (HGH) and insulin-like growth factor (IGF-1) are currently undetectable. And this does not begin to address other current and emerging synthetic blood boosting techniques being used by cyclists.

It seems that anti-doping agencies are happy to assert that they are winning the war on doping while neglecting issues such as biogeneric/biosimilar erythropoietin (EPO) stimulating proteins (ESPs); blood oxygen carriers: perfluorocarbon emulsions (PFCEs) and hemoglobin based oxygen carriers (HBOCs); hydroxyethylstarch (HES/HAES); and before long, if not already, EPO-mimetic peptide (EMPs). Read the rest of this entry »

EPO molecule

A BBC investigation suggests that most athletes who use recombinant human erythropoietin (EPO) continue to get away with it. The investigative article reveals several reasons why the EPO test is failing. But the BBC revealed that the biggest problem is not the ineffectiveness of the existing EPO tests used by the World Anti-Doping Agency (WADA). It is a lack of testing for variants of EPO.

Athletes are using various “biosimilar” EPO agents for which WADA has not yet developed a detection method. WADA’s ballyhooed test for the previously undetectable Mircera (pegylated EPO) was an admission that the already flawed existing EPO test was unable to detect variants of EPO; the announcement of the new CERA (Mircera) test at the 2008 Tour de France was considered a major victory.

There are also dozens of “copycat” or “biosimilar” versions of EPO. These are variants of EPO that are produced by different methods or exist as slightly different biological forms of EPO e.g. darbepoetin alfa, epoetin alfa, epoetin beta, epoetin gamma, epoetin delta, epoetin epsilon, epoetin zeta, epoetin theta, epoetin kappa, epoetin omega. The existence of biosimilar versions of EPO is a major problem for drug testers Read the rest of this entry »

Spanish doctor Marcos Maynar steroid expert

Spanish doctor Marcos Maynar Mariño sent an email offering comprehensive urinalysis and steroid profiling at 50 euros per athlete to as many as ten professional cycling teams including Gerolsteiner, Milram, CSC and Columbia . Maynar offered to provide a complete analysis consistent with the same control methods used by the International Cycling Union (UCI). The services would be conducted by the Laboratory of Analytical Chemistry at the Faculty of Sciences at the Universidad de Extremadura in Cáceres, Spain (“Dos médicos españoles, acusados de dopar,” July 20).

According to the German television station ARD, Spanish doctor Marcos Maynar offered these services as for internal testing allowing athletes to monitor their doping to ensure that their use of performance enhancing drugs would not be detected by doping controls at the 2008 Tour de France and other pro cycling events. Maynar responded to the allegations that he aided and abetted doping by suggesting that ARD had ulterior motives stemming from bitterness over disgraced cyclist Jan Ullrich (“Marcos Maynar niega que quiera favorecer el dopaje,” July 21).

“Since Jan Ullrich’s tested positive, the Germans have wanted to shit on the Spaniards.”

Read the rest of this entry »

2008 Tour de France 

The French National Anti-Doping Agency (AFLD) has been utlizing a secret new anti-doping test for a previously undetectable performance-enhancing drug during the 2008 Tour de France. Rumors about a test for Mircera started circulating when cyclist Riccardo Ricco failed his doping protocol. The World Anti-Doping Agency (WADA) quickly confirmed the rumors.

WADA gave notice to cyclists competing at the 2008 Tour de France that they were now able to detect the performance enhancing drug Mircera (methoxy polyethylene glycol-epoetin beta), a third generation version of erythropoietin (EPO) belonging to the category of drugs known as Continuous Erythropoeitin Receptor Activators (CERA).

Doping experts concerned with the fairness of the doping protocols administered by WADA-accredited labs were quick to raise questions about the new CERA doping detection methods Read the rest of this entry »