The Canadian Football League (CFL) is the only professional sporting league in North America that has not yet implemented steroid testing for its football players. Former WADA chief Dick Pound had previously called the CFL a “summer camp” for NFL players suspended for violations of the NFL policy on anabolic steroids and related substances (”WADA chief Pounds on CFL,” October 19, 2006).
“We’ve got the CFL,” Pound said. “It’s like a bad scene from the NHL. They say, ‘We don’t test in the Canadian Football League because we don’t need to test — there’s no drug use.’ Helloooo. We’re like a refuge for all the Americans… a summer camp for NFL players who have been suspended for drug use.”
The National Football League apparently is willing to jeopardize the health of its players in a misguided effort to catch athletes who use banned performance enhancing subtances. John Lombardo, M.D., the administrator and medical advisor to the NFL Policy regarding Anabolic Steroids and Related Substances allegedly knew that the dietary supplement StarCaps were contaminated with bumetanide as early as 2006. Bumetanide is a powerful prescription diuretic found in StarCaps but not disclosed by the manufacturer. Yet, he failed to notify any NFL teams about the discovery to prevent athletes from using StarCaps as an explanation for a positive bumetanide test result exposing NFL players to significant health risks that could have easily been prevented by responsible concern for players’ health and well-being as the primary objective.
Cornwell contends that Dr. John Lombardo, the administrator of the NFL’s policy regarding anabolic steroids and related substances, testified during the hearing that he learned in late 2006 of the presence of Bumetanide in StarCaps. Lombardo, per Cornwell, did not share this information with NFL players, because Lombardo feared that other players testing positive for Bumetanide would claim that they were taking StarCaps, even if they weren’t.
Says Cornwell: “Dr. Lombardo’s failure to disclose what he knew about StarCaps may have exposed NFL players to the significant health risks associated with the unintentional ingestion of diuretics.If Dr. Lombardo had notified NFL players that StarCaps contained bumetanide, Will, Deuce and Charles would have never used the product to lose weight.”
John Lombardo has previously notified teams of supplements that may cause NFL players to fail a drug test even when the banned substance was fully disclosed on the product labels. Why did he not notify players about the great threat of an UNDISCLOSED prescription drug in supplements that may have been used by NFL players!?!
understanding the currently available methods for identifying use of hGH and understanding the viability of urine testing for hGH in the future;
building a consensus on the most effective methods of implementing widespread blood testing for abuse of hGH;
identifying future strategies for hGH testing; and
understanding the United States Laws regarding the regulation and distribution of hGH
The current state of HGH testing involves blood testing. Anti-doping expert Don Catlin supervised growth hormone testing at the 2008 Beijing Olympics which involved approximately 1,000 blood samples; no athlete tested positive for HGH. In fact, no athlete has ever tested positive for human growth hormone using this test which has led many experts to question the effectiveness of the test (”Officials Question a Blood Test That Is Never Positive,” November 10)
Three hours into a conference held Monday by Major League Baseball on human growth hormone, the real question of the day emerged when officials from the commissioner’s office and the players union wondered aloud about how effective the current blood test for human growth hormone was if no one had tested positive.
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Osquel Barroso, the senior manager of science for the World Anti-Doping Agency, was one such expert invited to the conference. WADA, which oversees the testing of Olympic athletes, has tested 8,500 athletes for human growth hormone since 2000 and has never had a test come back positive.
The big news at the Growth Hormone Summit was the increasingly viable urine test for human growth hormone that utilizes nanotechnology to identify urinary HGH markers. Don Catlin, CEO of Anti-Doping Research and Professor Emeritus at the UCLA School of Medicine is collaborating with Lance Liotta, MD, PhD of George Mason University to validate the utility of this test for WADA
Anti-doping expert Don Catlin believes the numerous NFL players who tested positive for the diuretic butemanide may have unknowingly used dietary supplements tainted with the drug. (”Alleged use of old-school drug surprises experts,” October 29).
“I’d love to know,” said Don Catlin, a renowned expert who ran America’s first anti-doping lab. “But that’s why the first thing I thought was, ‘They take supplements all the time. Every athlete does. Maybe it’s a bad batch of supplements.’”
We reported previously at Catlin’s bewilderment at the intentional use of butemanide by NFL players as a masking agent for anabolic steroids. There were several plausible indicators that a contaminated supplement could have been the culprit. Experts are indeed baffled by the presence of an old and dangerous drug in anti-doping samples.
Two professional soccer players tested positive for the banned performance enhancing substances androstatriendione (ATD) and metabolites of the anabolic steroid boldenone according to the MLS. Red Bulls Jon Conway and Jeff Parke were suspended and fined ten percent of their respective salaries for violating the MLS substance abuse and behavioral health policy (SABH).
According to Red Bulls manager director Erik Stover, both players said “that they ingested an over-the-counter supplement that unknowingly contained a banned substance.”
The statement seems to imply that there was no indication that the banned substance androstatriendione (ATD) was listed on the label of the OTC supplement product. Most likely androstatriendione was listed with a synonymous chemical name e.g. 3,17-dioxo-etiochol-1,4,6-triene or 3 17-keto-etiochol-triene. Ignorance or naivete regarding supplement ingredients by drug-tested athletes rarely succeeds in exonerating them from anti-doping policy violations.
Products containing androstatriendione (ATD) are very popular in the sports nutrition marketplace. One of the most popular products in this category is Gaspari Nutrition’s Novedex XT. Novedex XT is, by all accounts, completely legal and DSHEA-compliant with all ingredients fully disclosed on the label. But if the anti-doping policy in an athlete’s sport has banned androstatriendione (ATD), then athletes would be wise to avoid all OTC supplements containing any and all modified or derivative versions of 1,4,6-androstatriene-3,17-dione (ATD).
Four of the eight NFL football players whose names were “leaked” as having violated the league’s policy on anabolic steroids and related substances were caught using the diuretic Bumex (bumetanide). New Orleans Saints running back Deuce McAllister and defensive ends Will Smith and Charles Grant tested positive for bumetanide as did Houston Texans deep snapper Bryan Pittman.
Reports of a “rash of positive steroid tests” in the NFL by news websites here and here and here and here are highly misleading and false since none of the players are alleged to have tested positive for steroids by the NFL. Nonetheless, MSNBC stated that one player tested positive for anabolic steroids with the headline ”Report: Saints’ McAllister positive for steroids“, but deep in the article reported the truth that it was bumetanide. There are even plausible indications these may have involved inadvertent doping from weight loss supplements tainted with bumetanide.
The proposed anti-doping tool would ask the athlete various questions about their own self-reported doping, hypothetical doping scenarios, and the doping behavior of other athletes. If the athlete’s responses to the questionnaire fit the psychological profile of a doper, then this might represent evidence that athlete is doping even if the athlete does not admit to doping! The research is based on the False Consensus Effect from social psychology research.
Researcher Jason Thomas, a graduate student in the doctoral program for synthetic organic chemistry at City University in New York, takes us inside the mind of a designer steroid chemist in an interview with Culturekiosque. Thomas describes a powerful tool that has the potential to create an infinite number of undetectable, designer anabolic steroids.
Once steroid designers specify the essential features and desired biological activity for steroid drug design, hundreds of novel designer steroids could be synthesized or simulated through Dynamic Combinatorial Chemistry (DCC) ["Designer Steroids: Speeding Evolution (and Filling Stadium Seats)" August 8].
Until now, human attempts to change testosterone’s anabolic, androgenic or estrogen-related properties have been relatively slow due to the fact that they have been addressed one at a time. A steroid designer imagines a certain compound, synthesizes it, and then tests it for effectiveness. This can take a matter of weeks or years. However, this process is about to undergo a drastic change. Dynamic Combinatorial Chemistry is a complicated process, so instead of explaining how it works I will simply provide the bottom line. Once steroid chemists have invested the necessary time into the chemical strategy for DCC, hundreds of novel steroid compounds can be synthesized and tested within a matter of minutes. The entire process is orchestrated by computers. The pharmaceutical sector has recently employed this process, and steroid manufactures will soon follow suit, if they haven’t already.
The Hellenic Olympic Committee (HOC) president believes organized doping is behind the fifteen Greek athletes who have failed anti-doping tests before and during the 2008 Beijing Olympics. Former 400-meter hurdles champion Fani Halkia, swimmer Ioannis Drymonakos, 400-meter runner Dimitrios Regas, sprinter Tassos Gousis and eleven unidentified Greek weightlifters all tested positive for the same prohibited anabolic steroid - methyltrienolone (”HOC president: Greek sports face organized doping,” August 18).
“There are 15 people, all with the same substance. This is the strangest thing, because it leads to the conclusion that there is an organized effort,” Minos Kyriakou told The Associated Press. The athletes — 11 weightlifters, three runners and a swimmer — all tested positive for methyltrienolone, a banned steroid. “There is an organized crime — because that is what this is called,” Kyriakou said. “Because it seems there is a lot of money hidden there, a lot of profit.”
Stuart P. Cram, strategic marketing vice president at Thermo Fisher, reports that their company has numerous service engineers available 24 hours a day during the Beijing Olympics to maintain uninterrupted and efficient operation of the Thermo Fisher testing equipment. Chinese Anti-Doping Agency purchased several products from their company including:
(2) Thermo Fisher DFS Sector Field gas chromatography/mass spectrometry (GC/MS) systems;
(1) Thermo Fisher Delta V isotope ratio mass spectrometer - used to distinguish between “natural and synthetic steroids”;
Agilent Technologies supplies the China Anti-Doping Agency with the majority of their steroid testing and drug detection equipment. Stephen B. Crisp, international business development manager at Agilent, states that Agilent also has technicians available 24/7 to maintain the operational status of Agilent equipment that includes 18 liquid/mass stations and 19 gas/mass stations.
